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Home • Teaching All LIRAD personnel are involved in research and, in addition, we have a special team made up of researchers: PhD graduates, pre-doctoral scholarship holders and technicians who carry out ten research projects financed by highly respected Catalan (Marató), Spanish (FIS, CICYT and Genoma España), European (Fifth and Sixth Framework Programme) and US (Juvenile Diabetes Research Foundation International) research bodies. All this has led to our recognition as a consolidated DGR-DURSI research group. Our research areas are: Clinical and experimental tolerance and immunotherapy. Development and innovation of diagnostic and molecular immunology. Clinical and epidemiological research in diagnostic immunology,    transplants and immunogenetics. Ongoing projects   Novel approaches to pathogenesis, diagnosis and treatment of autoimmune diseases based on new insights into thymus-dependent self-tolerance (Eurothymaide, FW6 2004-2009)   Person in charge (IP): Dr. Ricard Pujol Borrell   Thymic mechanisms of tolerance to peripheral antigens dependent on the AIRE gene: paper on common organ-specific autoimmune diseases and bases for new approaches (CiCyt 2006-2008)   Person in charge (IP): Dr. Ricard Pujol Borrell   Molecular danger signals and tertiary lymphoid tissue in thyroid autoimmunity and primary Sjogren's syndrome (2003-2006)   Person in charge (IP): Dr. Ricard Pujol Borrell   RNA interference as preventive therapy in experimental autoimmune experimental diabetes (FIS 2005-2007)   Person in charge (IP): Dr. Marta Vives Pi   Patterns of chemokines and their receptors involved in the advance of autoimmune diabetes (FIS 2002-2005)   Person in charge (IP): Dr. Marta Vives Pi   Role of nervous system Reactiva-B-Lymphocytes in the course of Type 1 diabetes (JDRF 2005-2008)   Person in charge (IP): Dr. Joan Verdaguer Autonell   Characterisation of B-lymphocytes which initially infiltrate pancreatic islets and those with APC function on autoreactive T-lymphocytes in Type 1 diabetes mellitus. Identification of autoantigens which recognise (FIS 2004-2007)   Person in charge (IP): Dr. Joan Verdaguer Autonell   Paper on exosomes in communication between antigen-presenting cells. Possible implications in the immune response (FIS 2004-2007)   Person in charge (IP): Dr. Francesc Enric Borràs Serres   Generation and use of dendritic cells for inducing tolerance of their own antigens (FIS 2002-2005)   Person in charge (IP): Dr. Francesc Enric Borràs Serres   Repercussions of the genetic structure of CCL4 (MIP-1ß) in the natural history and physiopathology of HIV infection. Implication of the polymorphism of SCYA4L (codified for CCL4L and another 9 alloforms) and relationship with other determining polymorphisms in AIDS (FIPSE 2005-2008)   Person in charge (IP): Dr. Manel Juan i Otero   Function and regulation of expression of the ISO- i alloforms of MIP-1ß (CCL4) in the immune response. Differential aspects in peripheral autoimmunity and on potentially regulatory T CD25+ lymphocytes (FIS 2002-2005)   Person in charge (IP): Dr. Manel Juan i Otero   Association of chemokine genetic polymorphisms and their receptors with the risk of rejection in lung transplants (FIS 2002-2005)   Person in charge (IP): Dr. Eduard Palou Rivera   Immunology mechanisms involved in the pathology of thyroid autoimmunity disease, regulatory cells and molecular danger signs (FIS 2006-2008)   Person in charge (IP): Dr. Anna Sanmartí / Dr. Eva Maria Martínez-Cáceres Help associated with the Networks   TRANSPLANT NETWORK:Strategies to optimise donation and transplant results   Person in charge of node: Dr. Ricard Pujol Borrell   AUTOIMMUNITY NETWORK   Person in charge of node: Dr. Ricard Pujol Borrell   Recognition as consolidated group: GROUP RESEARCHING REGULATION OF THE NORMAL AND PATHOLOGICAL IMMUNE RESPONSE   Person in charge Dr. Ricard Pujol Borrell Top

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